I found these news items about the hidden dangers of hotel rooms, disturbing.
the glasses in your room, are they really clean?
how about bed bugs and other germs?
are those actually clean sheets?
What was disturbing about the news items was the impression it gave of the 'dangers' so out of proportion to the actual risk, which is pretty much minimal.
People who might have become worried to the point of compulsive obsessive about cleanliness should try backpacking and staying in budget hostels.